1. Identification
Records identified via database search: 4,820 (PubMed: 2,140, Embase: 1,650, Cochrane: 1,030)
Duplicates removed prior to screening: 1,240
2. Screening
Records screened by title and abstract: 3,580
Records excluded by inclusion criteria: 3,210
3. Eligibility
Full-text reports assessed for eligibility: 370
Excluded: 328 (Inappropriate population: 140, Missing primary endpoint: 188)
4. Included Studies
New studies included in systematic review and quantitative synthesis: 42 studies (n=8,420)
PRISMA 2020 AuditedAutomated PRISMA Diagrams
Generate high-resolution vector flowcharts that conform exactly to PRISMA 2020 statement standards.
Risk of Bias Grading
Built-in Cochrane RoB 2 and ROBINS-I templates for systematic risk-of-bias scoring across clinical trials.
Synthesis Narrative Generator
Draft thematic synthesis chapters linking findings chronologically, conceptually, and methodologically.
Export to RevMan & Covidence
One-click export into standard review software for peer-review submission.